A safety and efficacy study provided experience on the use of zyvox in pediatric patients for the treatment of nosocomial pneumonia, complicated skin and skin structure infections, and other infections due to gram-positive bacterial pathogens, including methicillin-resistant and -susceptible staphylococcus aureus and vancomycin-resistant enterococcus faecium.
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the safety of zyvox formulations was evaluated in 2046 adult patients enrolled in seven phase 3 comparator-controlled clinical trials, who were treated for up to 28 days.
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the pharmacokinetics of zyvox and its two metabolites have also been studied in patients with end-stage renal disease esrd receiving hemodialysis.
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